The term "large size" refers to a clothing size that is significantly larger than average. In general, large-size clothing is designed for individuals who have a higher body weight or greater muscle mass than the typical person. The specific measurements and definitions of what constitutes a large size can vary depending on the brand or manufacturer, but it generally refers to pants with waist sizes ranging from 38 inches up to around 50 inches, and shirt sizes that range from extra-large to 6XL or even larger.